Introducing

National Institutes of Biotechnology Malaysia Publications

Research Publications

NoTitle of ArticleAuthors1st Author, Co-Author, Corresponding AuthorJournal Name (Full)DOI (url)
1Aptamer based immunotherapy: a potential solid tumor therapeuticSarmilah Mathavan, Yew Joon Tam, Khairul Mohd Fadzli Mustaffa and Gee Jun TyeGee Jun TyeFrontiers in Immunologyhttps://doi.org/10.3389/fimmu.2025.1536569
2Microemulsion-based formulation of enterocin CC2: a novel antimicrobial solution targeting Streptococcus mutansZhang Jin Ng Choon Fu Goh Ana Masara Ahmad Mokhtar Rozi Nuraika Binti Ramli Chee Keong Lee. Joo Shun TanDrug Delivery and Translational Researchhttps://doi.org/10.1007/s13346-025-01823-x
3Advancement in diagnostic approaches for latent tuberculosis: distinguishing recent from remote infectionsYi En Ding, Matthew Tze Jian Mohd Nor Norazmi, Balakrishnan, Gee Jun Tye Wong, VenugopalGee Jun TyeOne Health Outlookhttps://doi.org/10.1186/s42522-025-00144-w
4Establishment of High-Throughput Screening Assay using 384-Well Plate for Identification of Potent Antioxidants from Malaysian Local Plants Repository and Phytochemical Profile of Tetracera scandensAmyra Amat Sain, Azimah Amanah, Mohd Hasnan Mohd Noor, Wai Kwan Lau, Olalere Olusegun Abayomi and Zafarina ZainuddinTropical Life Sciences Researchhttps://doi.org/10.21315/
5Spatiotemporal mapping of canine rabies transmission dynamics in Sarawak, East Malaysia from 2017 to 2023Wada Y.A., Noordin M.M.; Mazlan M.; Ramanoon S.Z.; Izzati U.Z.; Lau S.F.; Mohd-Lila M.A.Tropical Biomedicinehttps://msptm.org/files/Vol42No1/tb-42-1-006-Wada-Y-A.pdf
6Development of an innovative approach for early diagnosis of cervical cancer using TCR-like antibodies targeting HPV18 E6 and E7 peptidesSachit, Bassam Ali; Dass, Sylvia Annabel; Rajan, Rehasri Selva; Tye, Gee Jun; Balakrishnan, VenugopalMolecular Medicine Reportshttps://doi.org/10.3892/mmr.2025.13583
7Stem cell derived exosome trilogy: an epic comparison of human MSCs, ESCs and iPSCsMalik, Siti Zawiah Abdul; Muhilan, Yugashini; Nordin, Fazlina; Ng, Min Hwei; Law, Jia Xian; Imran, Siti A. M.; Idris, Izyan Mohd; Tye, Gee JunStem Cell Research and Therapyhttps://doi.org/10.1186/s13287-025-04440-0
8Current photodynamic therapy and emerging synergies in oncologyThangeswaran, Danesh; Chin, Ding Sheng; Balakrishnan, Venugopal; Sreenivasan, Sasidharan; Lai, Hung Wei; Tye, Gee JunTye, Gee JunAsia-Pacific Journal of Molecular Biology and Biotechnologyhttps://doi.org/10.35118/apimbb.2025.033.2.03
9Influence of glycerine pitch on the metabolite profiling and enzyme activity in the poly(3-hydroxybutyrate- co-4-hydroxybutyrate) biosynthesis by Cupriavidus malaysiensis USMAHM13Amarajothi, Asha Devi; Abdullah, Amirul Al-Ashraf; Ramachandran, HemaMalaysian Journal of Microbiologyhttps://doi.org/10.21161/mim.230528
10Free-roaming dog population and density in Klang Valley, Peninsular Malaysia: A comparative enumeration method for improved management and rabies controlYunusa Adamu Wada, Mazlina Mazlan, Mustapha M. Noordin, Mohd Azmi Mohd-Lila, Lau Seng Fong, Siti Zubaidah Ramanoon, Nurul Izzati Uda ZahliMustapha M. NoordinPreventive Veterinary Medicinehttps://doi.org/10.1016/j.prevetmed.2025.106536
11Nanobodies targeting cytokines for the amelioration of autoimmune diseasesVijayandran, Kausalyah; Abdo, Ahmad Ismail Khaled; Wong, Matthew Tze Jian; Balakrishnan, Venugopal; Fazlina, Nordin Binti; Wan Kamarul Zaman, Wan Safwani; Lim, Crystale Siew Ying; Tye, Gee JunTye, Gee JunInternational Immunopharmacologyhttps://doi.org/10.1016/j.intimp.2025.115368
12Immune profiling in oncology: bridging the gap between technology and treatmentRavi, Nanthini; Tye, Gee Jun; Dhaliwal, Satvinder Singh; Musa, Muhammad Yusri; Wong, Matthew Tze Jian; Lai, Ngit ShinMedical Oncologyhttps://doi.org/10.1007/s12032-025-03002-x
13Detection of SARS-CoV-2 Delta, Omicron and XBB variant using colorimetric reverse-transcription loop-mediated isothermal amplification and specific primersKHENG OON LOW, NURHEZREEN MD IQBAL, AZRIN AHMAD and NOR AZFA JOHARIKheng Oon LowWORLD ACADEMY OF SCIENCES JOURNALhttps://doi.org/10.3892/wasi.2025.338
14Dataset of a complete genome sequence of Vibrio owensii v2 isolated from diseased Sabah’s red algae seaweed, Kappaphycus alvareziiNur Athirah Yusof, Vernon Vest Mangun; Wilson Thau Lym Yong; Mohd Faizal Abu BakarData in Briefhttps://doi.org/10.1016/j.dib.2025.111447
15Lactococcus lactis subsp. Lactis Isolated From Soil of Basil Plant With Antimicrobial Activity Against Bacterial Leaf Blight Causal Agent Xanthomonas oryzae pv. Oryzae and Pantoea ananatisAmalia Mohd Hashim, Nur Nadia Nabilah Mohd Basri, Ahmad Zuhairi Abdul Malek, Mohd Hafis Yuswan Yusuf, Noor Baity Saidi, Dzarifah Zulperi, Wan Nur Ismah Wan Ahmad Kamil, Fairolniza Mohd Shariff, Nur Fadhilah Khairil Mokhtar, Mohd Faizal Abu BakarScientific ReportsNo DOI
16Optimizing E. coli production of oil palm pla1-3 lipase through recombinant technologyFatin Fathiah Safiudin; Chee Fah Wong; Zatty Syamimi Adura Mat Said; Ummirul Mukminin Kahar; Iffah Izzati Zakaria; Nurniwalis Abdul WahabAsia-Pacific Journal of Molecular Biology and Biotechnology10.35118/apimbb.2025.033.1.11
17Purification and characterisation of Bile-salt activated lipase (BSAL) enzyme from bovine (Bos taurus) pancreasNur Hidayah Reshidan; Norliza Bahtiar Affendy; Mohd Anuar Jonet; Dhilia Uddie Lamasudind; Zaidah Zainal Ariffin; Mazatulikhma Mat Zaina; Umi Marshida Abd Hamida;Asia-Pacific Journal of Molecular Biology and Biotechnologyhttps://doi.org/10.35118/apimbb.2025.033.1.12
18Skin-penetrating peptides (SKPs): Enhancing skin permeation for transdermal delivery of pharmaceuticals and cosmetic compoundsAmeerah Montree Muhammad, Alif Ismail, Pei Pei Chong, Wei Hsum Yap, Azira Muhamad, Noorjahan Banu Alitheen, Antony Kam, Shining Loo, Khai Wooi LeeInternational Journal of Pharmaceuticshttps://doi.org/10.1016/j.ijpharm.2025.125339
19Metabolic clues to memory loss: High-fat diets and brain-adipose crosstalk in zebrafishFarah Mejbel Al Jaberi, Ragdha Alzarzour, Aidiahmad Dewa, Azira Muhamad, Fauziahanim ZakariaBehavioural Brain Researchhttps://doi.org/10.1016/j.bbr.2025.115559
20Genetic screening of malay familial hypercholesterolemia patient for LDLRAP1/PCSK9/APOB mutations via whole exome sequencingMuhammad-Redha Abdullah-Zawawi, Zam Zureena Mohd Rani, Nur Syakeera Seeni Ahamed Mydeen, Ryia Illani Mohd Yunos, Siti Aishah Sulaiman, Izzatul ‘Aliaa Badaruddin, Rose Ismet, Norlaila Mustafa, Syahidatun Najwa Abu Zahid, Rahman Jamal, Azrul Azlan Hamzah, Nor Azian Abdul MuradEgyptian Journal of Medical Human Geneticshttps://doi.org/10.1186/s43042-025-00673-z.
21Bioinformatics-driven identification of key non-invasive prognostic biomarkers in hepatocellular carcinomaMuhammad-Redha Abdullah-Zawawi, Muhammad Irfan Abdul Jalal, Shing Cheng Tan, Loscheni Varma, Nur Alyaa Afifah Md Shahri, Mira Farzana Mohamad Mokhtar, Ryia Illani Mohd Yunos, Nurul Syakima Ab Mutalib, Rahman JamalEgyptian Journal of Medical Human Geneticshttps://doi.org/10.1186/s43042-025-00714-7
22Translocating shRNA: a novel approach to RNA interference with Newcastle Disease Virus as Viral VectorWei Chin Koh, Khatijah Yusoff, Adelene Ai-Lian Song, Norazalina Saad, Tiong Kit Tan, Pheik-Sheen Cheow, Suet Lin ChiaSuet Lin ChiaJournal of General Virologyhttps://doi.org/10.1099/jgv.0.002127
23Structural and Biochemical Insights into GMHpaB: A Thermostable 4-Hydroxyphenylacetate-3-Monooxygenase with Dual Cofactor VersatilityNor Asyikin Che Husain; Azyyati Mohd Padzil; Azney Zuhaily Md. Taib; Nurulusna Che Zain; Mohd Faizal Abu Bakar; Kyle S. Gregory; K. Ravi Acharya; Mohd Anuar Jonet; Haryati JamaluddinInternational Journal of Biological Macromoleculeshttps://doi.org/10.1016/j.ijbiomac.2025.146065
24Aptamer-Based Diagnostics and Therapeutics in Viral Sepsis: Current Progress, Application and Future ProspectsNoraini Abd-Aziz; Fatimah Ibrahim; Sun Tee TayNoraini Abd-AzizCurrent Research in Biotechnologyhttps://doi.org/10.10.1016/j.crbiot.2025.100318
25Hairpin in a haystack: In silico identification and characterization of plant-conserved microRNA in RafflesiaceaeWicaksono, Adhityo; Meitha, Karlia; Wan, Kiew-Lian; Mat Isa, Mohd Noor; Parikesit, Arli Aditya; Molina, JeanmaireOpen Life Scienceshttps://doi.org/10.1515/biol-2022-1033
26Investigation of the Clustering of High Quality Stingless Bee Honeys using Unsupervised Machine Learning ModelsYusoff, Yusnaini Md; Poongavanam, Nalinah; Latip, Jalifah; Mamat, Mohd Razif; Joe, Lim Seng; Din, Wardah Mustafa; Jambari, Dian IndrayaniMalaysian Journal of Chemistryhttps://doi.org/10.55373/michem.v27i1.110
27Genomic insights into the biogeography and evolution of Galápagos iguanasParadiso, Cecilia; Gratton, Paolo; Trucchi, Emiliano; López-Delgado, Julia; Gargano, Marco; Garizio, Lorenzo; Carr, lan M.; Colosimo, Giuliano; Sevilla, Christian; Welch, Mark E.; Firdaus-Raih, Mohd; Noor Mat-Isa, Mohd; Goodman, Simon J.; Gentile, GabrieleMolecular Phylogenetics and Evolutionhttps://doi.org/10.1016/i.ympev.2025.108294
28Bioprospecting waste for polyhydroxyalkanoates production: embracing low carbon bioeconomyAbbas, M.I.; Amelia, T.S.M.; Bhubalan, K.; Vigneswari, S.; Ramakrishna, S.; Amirul, A.A.A.International Journal of Environmental Science and Technologyhttps://doi.org/10.1007/s13762-024-05831-1
29Viral interference during coinfection and sequential infection of enterovirus A71 and coxsackievirus A16Chang, Hooi Yee; Ong, Kien Chai; Jasni, Kartini; Abdullah, Syahril; Ong, Yin Jie; Sam, I-Ching; Chan, Yoke FunVirologyhttps://doi.org/10.1016/i.virol.2025.110610
30Characterization of the host specificity of the SH3 cell wall binding domain of the staphylococcal phage 88 endolysinTham, Hong Yun; Chong, Li Chuin; Krishnan, Melvina; Khan, Asif Mohammad; Choi, Sy Bing Tamura, Takashi; Yusoff, Khatijah; Tan, Geok Hun; Song, Adelene Ai-LianArchives of Microbiologyhttps://doi.org/10.1007/s00203-025-04242-1
31Voltammetric-based immunosensing of Newcastle disease virus on polyethylene glycol-containing self-assembled monolayer modified gold electrodeAbd Muain, Mohamad Farid; Amir Hamzah, Syahir; Chia, Suet Lin; Yusoff, Khatijah; Lim, Hong Ngee; Shinya, Ikeno; Ahmad Amir Tajudin, AsilahYusoff, KhatijahAnalytical Biochemistryhttps://doi.org/10.1016/j.ab.2024.115700
32Interferon-Gamma And Interleukin-10 Genetic Polymorphisms Among the Pulmonary Tuberculosis Caused by Malaysia-Specific Mycobacterium Tuberculosis Strain: SIT745/EAI1-MYSNik Zuraina, Nik Mohd Noor; Mohd Sedi, Nur Annisa Nasuha; Goni, Mohammed Dauda; Mohamad, Suharni; Norazmi, Mohd Nor; Suraiya, SitiNorazmi, Mohd NorPeerJhttps://doi.org/10.7717/peeri.19576
33A 22 month prospective assessment of neutralizing and IgG antibody levels against SARS-CoV-2 variants following homologous and heterologous BNT162b2 boostingMat Yassim, Aini Syahida; Mohd Hisham, Anis Atifah; Nik Daud, Nik Nur Atiqah; Anuar, Nur Diana; Tan, Ti-Myen); Suppian, Rapeah; Siti Asmaa, Mat Jusoh; Mohamad Asri, Amiratul Aifa; Azlan, Maryam; Idris, Nur Suhaila; Muhamad, Rosediani; Norazmi, Mohd NorScientific Reportshttps://doi.org/10.1038/s41598-025-05377-3
34HOXA13 promotes immune evasion in bladder cancer by suppressing antigen processing and presentation, and phagosome pathwaysChin, Fee-Wai; Chan, Soon-Choy; Chau, De-Ming; Ong, Teng-Aik; Abdul Razack, Azad Hassan; Yusoff, Khatijah; Veerakumarasivam, AbhiFunctional and Integrative Genomicshttps://doi.org/10.1007/s10142-025-01553-w
35Effect of Domain Manipulation in the Staphylococcal Phage Endolysin, Endo88, on Lytic Efficiency and Host RangeKrishnan, Melvina; Tham, Hong Yun; Wan Nur Ismah, Wan Ahmad Kamil; Yusoff, Khatijah Song, Adelene Ai-LianMolecular Biotechnologyhttps://doi.org/10.1007/s12033-024-01216-4
36Viral vectors: design and delivery for small RNAKoh, Wei Chin; Yusoff, Khatijah; Song, Adelene Ai Lian; Saad, Norazalina; Chia, Suet LinJournal of Medical Microbiologyhttps://doi.org/10.1099/imm.0.001972
37Improving Peat Soil Quality for Chili Production Using Durian Pectin Microalgae in an Immobilization MatrixZainal, Nurin Hadirah; Mohd Fuzi, Siti Fatimah Zaharah; Hashim, Nor Haslina; Oon, Low Kheng; Matias, Hazel Monica Peralta; Abdullah, Shakila Binti; Khairuddin, FarahayuEnvironmental Quality Managementhttps://doi.org/10.1002/tqem.70220
38Soluble recombinant enterovirus 71 VP1 fused to truncated newcastle disease virus nucleoprotein elicits immune responses in miceMustafa, Suhaili; Abd-Aziz, Noraini; Yusoff, Khatijah Mohd; Shafee, NorazizahBrazilian Journal of Microbiologyhttps://doi.org/10.1007/s42770-025-01784-w
39Acoustic streaming on antibody-functionalized screen-printed electrode enhances detection sensitivity and total assay duration for voltammetric immunosensing of newcastle disease virusAbd Muain, Mohamad Farid; Amir Hamzah, Amir Syahir; Chia, Suet Lin; Yusoff, Khatijah Mohd; Lim, Hongngee; Ikeno, Shinya; Laurell, Thomas L.; Ahmad Tajudin, AsilahBioelectrochemistryhttps://doi.org/10.1016/j.bioelechem.2025.109043
40Delving deeper in the eye of the hurricane: Immunopathogenesis & molecular characterization of cytokine storm in COVID19-, association with disease severity & the therapeutic regimensMuzaffar, Umaiya; Shaik Fakiruddin, Kamal Shaik; Talebiashtiany, Yasaman; Abdullah, SyahrilAbdullah, SyahrilCytokinehttps://doi.org/10.1016/j.cyto.2025.157025
41Olaparib synergy screen reveals Exemestane induces replication stress in triple-negative breast cancerYusoh, Nur Aininie; Su, Liping; Chia, Suet Lin Tian, Xiaohe; Ahmad, Haslina; Gill, Martin R.Molecular Oncologyhttps://doi.org/10.10021878-0261.70/093
42Intertypic Recombination Between Coxsackievirus A16 and Enterovirus A71 Structural and Non-Structural Genes Modulates Virulence and Protection EfficacyChang, Hooi Yee; Tee, Hankang; Ong, Kienchai; Jasni, Kartini; Abdullah, Syahril; Sam, I. Ching; Chan, Yokefun Fun ChanVaccineshttps://doi.org/10.3390/vaccines13101017
43Draft genome sequence of Nitratireductor sp. PBL-C9-a marine bacterium encoding glycoside hydrolases isolated from Batu Laut Beach in Selangor, MalaysiaKahar, Ummirul Mukminin; Rahman, Nasibah Abdul; Sharoul, Nabila Aisyah; Ramzan, Farzana MuhammadKahar, Ummirul MukmininMicrobiology Resource Announcementshttps://doi.org/10.1128/mra.00683-25
44How does NMR support SARS-CoV-2 protein-ligand interaction studies?Mohmad Misnan, Norazlan; Muhamad, Azira; Mohd Abd Razak, Mohd Ridzuan; Lam, Kok WaiAnalytical and Bioanalytical Chemistryhttps://doi.org/10.1007/s00216-025-06081-x
45Immunomodulatory Role of Milk on Gut Microbiota: Implications for Enhancing Oral Vaccine EfficacyAsri, Nur Ain Mohd; Bushra, Solehah Mohd Rosdan; Asri, Amiratul Aifa Mohamad; Rapeah, S.; Norazmi, M. N.Norazmi, M. N.Probiotics and Antimicrobial Proteinshttps://doi.org/10.1007/s12602-025-10785-
46In vitro antiviral activity of Coriandrum sativum L. seed crude extracts against respiratory syncytial virusRamasamy, Darssheela; Ashaari, Nur Suhanawati; Yusof, Z. N.B.; Abdul-Wahab, Azimah; Zakaria, Iffah Izzati; Ismail, SailaAsia-Pacific Journal of Molecular Biology and Biotechnologyhttps://doi.org/10.35118/apimbb.2025033.3.09
47The ASEAN genome consortium: advancing equitable precision medicine through regional solidaritySasongko, Teguh Haryo; Gunadi; Hoh, Boon Peng; Minari, Jusaku; Seow, Shih Wee; Shotelersuk, VorasukThe Lancet Regional Health – Western Pacifichttps://doi.org/10.1016/j.lanwpc.2025.101611
48Salvianolic acid B ameliorates Aẞ42 toxicity in Aẞ42-expressing Drosophila model: behavioral and transcriptomic profilingTan, Florence Hui Ping; Azzam, Ghows; Najimudin, Nazalan; Shamsuddin, Shaharum; Zainuddin, Azalina; Kasihmuddin, Mohd Shareduwan MohdAzzam, GhowsMetabolic Brain Diseasehttps://doi.org/10.1007/s11011-025-01625-7
49Evaluation of methoxyflavones as dengue NS2B-NS3 protease inhibitors: an in silico and in vitro studiesNur Farhana Mustafa; Kian-Kai Cheng; Siti Aisyah Razali; Habibah A. Wahab; Nurul Hanim Salin; Iffah Izzati Zakaria; Muhammad Helmi NadriMolecular Diversityhttps://doi.org/10.1007/s11030-024-10899-5
50Discovery of azaleatin as a potential allosteric inhibitor for dengue NS2B-NS3 protease using in vitro and in silico studiesMustafa, Nur Farhana; Cheng, Kiankai; Nadri, Muhammad Helmi; Razali, Siti Aisyah; Zakaria, Iffah Izzati; Salin, Nurul Hanim; Amran, Syazwani ItriJournal of Biomolecular Structure and Dynamics10.1080/07391102.2024.2335296