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GlacIER: Glaciozyma antarctica Integrated Exploration Resource

GlacIER previously known as GanDB, stores the information of proteins found in G. antarctica. The annotation displays in GlacIER is based on experimental and in silico approach.


Taxonomy of G. antarctica:


Kingdom: Fungi

Subkingdom: Dikarya

Phylum: Basidiomycota

Class: Pucciniomycotina

Order: Microbotryomycetes

Family: Microbotryomycetes incertae sedis

Genus: Glaciozyma

Scientific Name: Glaciozyma antarctica



Collaboration

  1. Malaysia Genome Institute

  2. Universiti Kebangsaan Malaysia

  3. Universiti Sains Malaysia

  4. Universiti Teknologi Malaysia

  5. Universiti Malaysia Sabah


Database Release:

  1. GanDB v1.0: released on 16th Mac 2012

  2. GanDB v1.1: released on 11th June 2012

  3. GanDB v1.2: released on 6th June 2015

  4. GanDB v2.0: released on 9th September 2017

  5. GlacIER v1.0: released on 20th October 2020


Data Release Statement

This sequencing consortium plans on publishing the completed and annotated sequences in a peer-reviewed journal as soon as possible. Permission of the principal investigator(s) should be obtained before publishing analyses of the sequences/proteins/genes on a scaffold or genome scale.


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Publication


  1. Firdaus-Raih M, Hashim NHF, Bharudin I, Abu Bakar MF, Huang KK, Alias H, Lee BKB, Mat Isa MN, Mat-Sharani S, Sulaiman S, Tay LJ, Zolkefli R, Muhammad Noor Y, Law DSN, Abdul Rahmann SH, Md-Illias R, Abu Bakar FD, Najimudin N, Abdul Murad AM, Mahadi NM. (2018). The Glaciozyma antarctica genome reveals an array of systems that provide sustained responses towards temperature variations in a persistently cold habitat. PLOS ONE. 13(1): e0189947. [Link]

  2. Ramli AN, Mahadi NM, Rabu A, Murad AM, Bakar FD and Illias RM, (2011). Molecular cloning, expression and biochemical characterisation of a cold-adapted novel recombinant chitinase from Glaciozyma antarctica PI12. Microbial Cell Factories. 10(1):94. [Link]

  3. Ramli AN, Mahadi NM, Shamsir MS, Rabu A, Joyce-Tan KH, Murad AM and Illias RM, (2012). Structural prediction of a novel chitinase from the psychrophilic Glaciozyma antarctica PI12 and an analysis of its structural properties and function. Journal of Computer-Aided Molecular Design. 1-15. [Link]

  4. Alias, N., Ahmad Mazian, M., Salleh, A.B., Basri, M., and Rahman, R.N. (2014) Molecular Cloning and Optimization for High Level Expression of Cold-Adapted Serine Protease from Antarctic Yeast Glaciozyma antarctica PI12. Enzyme Research . 1-15. [Link]

  5. Hashim, N.H., Bharudin, I., Nguong, D.L., Higa, S., Bakar, F.D., Nathan, S., Rabu, A., Kawahara, H., Illias, R.M., Najimudin, N., Mahadi, N.M., and Murad, A.M. (2013) Characterization of Afp1, an antifreeze protein from the psychrophilic yeast Glaciozyma antarctica PI12.Extremophiles . 117(1):63-73. [Link]

  6. Jaafar, N.R., Littler, D., Beddoe, T., Rossjohn, J., Illias, R.M., Mahadi, N.M., Mackeen, M.M., Murad, A.M., and Abu Bakar, F.D. (2016) Crystal structure of fuculose aldolase from the Antarctic psychrophilic yeast Glaciozyma antarctica PI12.Acta Crystallographica. Section F, Structural Biology Communications . 72(11):831-839. [Link]

  7. Yusof, N.A., Hashim, N.H., Beddoe, T., Mahadi, N.M., Illias, R.M., Bakar, F.D., and Murad, A.M. (2016) Thermotolerance and molecular chaperone function of an SGT1-like protein from the psychrophilic yeast, Glaciozyma antarctica. Cell Stress Chaperones. 21(4):707-715. [Link]

Citing GlacIER

GlacIERproject. "Glaciozyma antarctica Integrated Exploration Resource" http://www.mgi-nibm.my/glaciozyma_antarctica/v2 (date of message or visit).

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Links

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Acknowledgement


    We acknowledge support given by the Australian Antarctic Division and the Malaysian Antarctic Research Programme (MARP) of the Malaysian Academy of Sciences.

Researchers


  1. Prof. Emeritus Dr. Nor Muhamamad Mahadi
  2. Assoc. Prof Dr. Abdul Munir Abdul Murad
  3. Mohd Noor Mat Isa
  4. Prof. Dr. Mohd Nazalan Mohd Najimudin
  5. Prof. Dr. Rosli Md. Illias
  6. Prof. Dr. Clemente Michael Wong
  7. Assoc. Prof. Dr. Firdaus Mohd Raih
  8. Assoc. Prof. Dr. Farah Diba Abu Bakar
  9. Dr. Khairina Tajul Arifin
  10. Dr. Amir Rabu
  11. Dr. Douglas Law Sie Nguong
  12. Dr. Noor Haza Fazlin
  13. Dr. Izwan Bharudin
  14. Dr. Nurul Hidayah Samsulrizal
  15. Dr. Nur Athirah Yusof
  16. Dr. Nardiah Rizwana Jaafar
  17. Dr. Nik Yusnoraini Yusof
  18. Halimah Alias
  19. Mohd Faizal Abu Bakar
  20. Mohd Khairi Mohd Nizar
  21. Nurul Huda Sapee
  22. Radziah Zolkefli
  23. Tay Lih Jinq
  24. Shuhaila Mat Sharani
  25. Suhaila Sulaiman
  26. Siti Aisyah Zakaria
  27. Huang Kie Kyon
  28. Mahzan Md Tab
  29. Yusuf Muhammad Noor
  30. Siti Hamidah Abd Rahman
  31. Amelia Zamri
  32. Fauziah Hanim Shaarani
  33. Akzam Saidin
  34. Govindaraj Sowmiya
  35. Vivien Junker

Database developers & curators


  1. Suhaila Sulaiman
  2. Shuhaila Mat Sharani
  3. Mohd Faizal Abu Bakar

Financial support


This work was supported by the Genomics and Molecular Biology Initiatives Programme of the Malaysia Genome Institute, MOSTI, Malaysia (grant number 07-05-MGI-GMB014).


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News

20-October-2020
Glacier v1.0 is released!
Structural Genomics feature added
09-September-2017
GanDB v2.0 is released!
New feature of GanDB updated
06-June-2015
GanDB v1.2 updated!
New link and sequence update on GanDB!
11-June-2012
GanDB v1.1 updated!
New sequence update on GanDB!
19-March-2012
GanDB v1.0 is released!
First release of GanDB

Information

Please cite GlacIER when referring to data accessed through this site.

Database Update

Please email your query to database administrators

mfaizal@nibm.my

Contact

Malaysia Genome Institute
Jalan Bangi
43000 Kajang
Selangor Darul Ehsan
Malaysia

E-mail: contact.mgi@nibm.my
Phone: +6 03 8926 7446
Fax: +6 03 8926 7972