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Learn More
HTMLText_9CCDF260_8585_365F_41E0_8BAFCB231067.html =
Welcome to Malaysia Genome Institute (MGI)
HTMLText_A1A9C234_858D_3627_41CF_8422DD381F08.html =
Learn More
HTMLText_B636F6F7_868F_CA74_41C7_4AFB380483B1.html =
AKTA Avant Protein Purification System


This is a preparative protein purification chromatography system that is used to isolate the protein of interest and purify them before we proceed to downstream processes.


Operated using the UNICORN
Software that is user friendly and easy for experimental design and method development.



HTMLText_C6DBD2F6_8680_4A74_41C5_0D61FB3E320B.html =
Beckman Benchtop Centrifuge


Small scale centrifuge used to
spin down samples.
HTMLText_BAB7176A_8680_4B9C_41B6_5039577B3C6A.html =
Biorad Heating Block


To heat samples for SDS-PAGE.
HTMLText_C20AB9B1_8683_C68C_41D5_BB1842273FD4.html =
Cold Room


The low temperature room will provide conducive purification environment to preserve the integrity of proteins and whole samples during the process. Doing experiment at lower temperature will help to reduce proteolytic activity and prevent unwanted degradation of our valuable biological samples.
This room also provide storage for crystal growth that need lower temperature to form crystal.
HTMLText_9595487B_8746_9690_41D1_4F7F890414CF.html =
ECOTRON INFORS HT


Compact Incubator Shaker – to grow microbial cultures expressing recombinant proteins or cells producing non-recombinant proteins.


Programmable temperature and agitation to produce optimum environment for cell growth.
HTMLText_B5B3DAD8_8687_BABC_41DB_3041C7DE9238.html =
Magnetic Stirrer


To mix the buffer during buffer preparation.
HTMLText_B31396AD_8680_4A94_41D7_AD4530E5BDFD.html =
Mettler Toledo pH meter


To adjust pH
for buffer preparation.
HTMLText_BAA27516_8680_4FB4_41C5_75CF5F9FCBA9.html =
Mini Spin


Low speed centrifuge for sample preparation.
HTMLText_A14718AF_8683_C694_41D7_9F2D59357075.html =
RUMED – Cooled Incubators


Is used to grow crystal seeds. It has a programme to control the temperature, lighting and humidity which is crucial for crystal growth.
HTMLText_A9A782FA_8680_4A7C_41BE_5904282B538F.html =
Refrigerator -20℃


storage for chemicals and research samples. Chemicals and samples used in Structural Biology and Crystallography that need to be stored at a low temperature are kept in this refrigerator.
HTMLText_BAA9B9D5_8680_46B4_41CA_DD2C016EA839.html =
Vortex Mixer


To mix buffers or samples using maximum shake force.
HTMLText_90DD562E_859F_7E23_41DE_A250C059943B.html =
National Institutes of Biotechnology Malaysia (NIBM)
is a consortium of three national biotechnology institutes – Malaysia Genome Institute (MGI), Agro - biotechnology Institute Malaysia (ABI) and Malaysian Institute of Pharmaceuticals & Nutraceuticals (IPHARM)
HTMLText_B636F6F7_868F_CA74_41C7_4AFB380483B1_mobile.html =
AKTA Avant Protein Purification System


This is a preparative protein purification chromatography system that is used to isolate the protein of interest and purify them before we proceed to downstream processes.


Operated using the UNICORN
Software that is user friendly and easy for experimental design and method development.
HTMLText_C6DBD2F6_8680_4A74_41C5_0D61FB3E320B_mobile.html =
Beckman Benchtop Centrifuge


Small scale centrifuge used to
spin down samples.
HTMLText_BAB7176A_8680_4B9C_41B6_5039577B3C6A_mobile.html =
Biorad Heating Block


To heat samples for SDS-PAGE.
HTMLText_C20AB9B1_8683_C68C_41D5_BB1842273FD4_mobile.html =
Cold Room


The low temperature room will provide conducive purification environment to preserve the integrity of proteins and whole samples during the process. Doing experiment at lower temperature will help to reduce proteolytic activity and prevent unwanted degradation of our valuable biological samples.
This room also provide storage for crystal growth that need lower temperature to form crystal.
HTMLText_9595487B_8746_9690_41D1_4F7F890414CF_mobile.html =
ECOTRON INFORS HT


Compact Incubator Shaker – to grow microbial cultures expressing recombinant proteins or cells producing non-recombinant proteins.


Programmable temperature and agitation to produce optimum environment for cell growth.
HTMLText_B5B3DAD8_8687_BABC_41DB_3041C7DE9238_mobile.html =
Magnetic Stirrer


To mix the buffer during buffer preparation.
HTMLText_B31396AD_8680_4A94_41D7_AD4530E5BDFD_mobile.html =
Mettler Toledo pH meter


To adjust pH
for buffer preparation.
HTMLText_BAA27516_8680_4FB4_41C5_75CF5F9FCBA9_mobile.html =
Mini Spin


Low speed centrifuge for sample preparation.
HTMLText_A14718AF_8683_C694_41D7_9F2D59357075_mobile.html =
RUMED – Cooled Incubators


Is used to grow crystal seeds. It has a programme to control the temperature, lighting and humidity which is crucial for crystal growth.
HTMLText_A9A782FA_8680_4A7C_41BE_5904282B538F_mobile.html =
Refrigerator -20℃


storage for chemicals and research samples. Chemicals and samples used in Structural Biology and Crystallography that need to be stored at a low temperature are kept in this refrigerator.
HTMLText_BAA9B9D5_8680_46B4_41CA_DD2C016EA839_mobile.html =
Vortex Mixer


To mix buffers or samples using maximum shake force.
HTMLText_90DD562E_859F_7E23_41DE_A250C059943B_mobile.html =
National Institutes of Biotechnology Malaysia (NIBM)
is a consortium of three national biotechnology institutes – Malaysia Genome Institute (MGI), Agro - biotechnology Institute Malaysia (ABI) and Malaysian Institute of Pharmaceuticals & Nutraceuticals (IPHARM)
HTMLText_9CCDF260_8585_365F_41E0_8BAFCB231067_mobile.html =
Welcome to Malaysia Genome Institute (MGI)
HTMLText_8ACCBC18_AE6E_5025_41AD_D0A3B5A42D5B.html =
NMR spectroscopy is a type of spectroscopy that allows chemists to see the structure of a molecule.


Malaysia Genome Institute is equipped with a Bruker Ascend 700 MHz NMR spectrometer


This spectrometer provides information on structural, dynamics and interactions of biomolecules and compounds.


NMR spectrometer is crucial in metabolomics studies (metabolomics is the large-scale study of small molecules, commonly known as metabolites, within cells, biofluids, tissues or organisms.



Person In Charge:
Name : Dr. Azira Muhamad
Email : aziramuhamad@nibm.my
Tel No. 03-89267446
HTMLText_89F672E0_8749_9BB0_41D7_888025A991FE.html =
Finally quality sets of collected data are combined computationally with complementary chemical information to obtain and refine a model from the arrangement of atoms within the crystal.
Crystal structure is obtained from the final refined model and usually will be deposited in crystallographic database (such in Protein Data Bank).




Person In Charge:
Name : Dr. Mohd Anuar bin Jonet
Email : anuarjonet@nibm.my
Hp No. 03-89267446
HTMLText_992FA788_867F_FEF3_41C0_169D2C1119FB.html =
The RapidRAW technology is developed based on protein precipitation principle for fake honey/ sugar syrup differentiation. This product offers low cost option for fake honey screening and honey quality monitoring for industry and consumer.


Advantage:
• Simple technique
• Rapid result (2 minutes)
• Suitable for on-site monitoring
• Qualitative analysis
• Detect fake honey


Market potential:
1- Cytotoxicity assay
• To detect possible fake product


2- Food safety monitoring
• First line screening to differentiate fake product.
• Can be indicative for protein content in honey



Person In Charge:
Name : Mohd Razif bin Mamat/Dr Nor azfa Johari
Email : razif@nibm.my/azfajo@nibm.my
Hp No : 019-3280097
HTMLText_B1C9BF14_AE63_D02D_41D2_9B2E2F9FB7B1.html =
This laboratory is the preparative area for research involving structural study. The provides platform for processing sample from protein crude extracts. Different purification techniques will be applied to remove contaminants prior to crystallization experiment.




Person In Charge:
Name : Dr. Mohd Anuar bin Jonet
Email : anuarjonet@nibm.my
Tel No. 03-89267446
HTMLText_B986BA06_AE22_502D_41DF_6F3D5FB46DC9.html =
We promote advancements in biology by providing researchers complete genomic solutions using state-of-the-art DNA and RNA analysis instruments. The instrument available range from traditional capillary sequencing (Sanger Technology) to next-generation sequencing (Illumina MiSeq® System). The facility is perfectly suited to cater your project needs whether whole genome sequencing (WGS), transcriptome sequencing, amplicon-based projects, metagenomics as well as targeted sequencing.


Illumina MiSeq® System
• Suitable for targeted gene sequencing, metagenomics, small genome sequencing, targeted gene expression, amplicon sequencing and library QC.
• Variable options suitable to any application with generation of raw data up to 15 Gb of output with 25 M sequencing reads and 2x300 bp read lengths.


Sanger DNA Sequencing
• The Applied Biosystems 3730xl is a fully automated system used for detecting fluorescently labelled DNA and can provide up to 800 high quality bases per reaction.
• Ideal for single sample sequencing, primer walking, shotgun sequencing SNP detection & genome finishing.


Person In Charge:
Name : Irni Suhayu Sapian
Email : suhayu@nibm.my
Tel No : 03-89267446
HTMLText_C9D3EF7A_8687_BA7C_41DF_8F860098093B.html =
X-ray diffractometer (XRD) is considered to be the most important tool for determining the three-dimensional crystal structures of atom and molecules at high-resolution.


Structures of biological macromolecular at the atomic resolution level will provide information of the atoms size and the length and types of chemical bonds.


Comprehensive information from X-ray crystallographic experiment will reveal the structure and function of many biological molecules, including vitamins, drug, protein, and nucleic acids, such as DNA.


Simple workflow in obtaining 3-dimensional structure of desired protein will start with:


1- Producing an adequate protein crystal with pure in composition.
2- The crystal is subsequently placed in finely focused monochromatic beam of X-rays.
3- The angle and intensities of diffracted X-rays are measured at different crystal orientations


Person In Charge:
Name : Dr. Mohd Anuar bin Jonet
Email : anuarjonet@nibm.my
Hp No. 03-89267446
HTMLText_8ACCBC18_AE6E_5025_41AD_D0A3B5A42D5B_mobile.html =
NMR spectroscopy is a type of spectroscopy that allows chemists to see the structure of a molecule.


Malaysia Genome Institute is equipped with a Bruker Ascend 700 MHz NMR spectrometer


This spectrometer provides information on structural, dynamics and interactions of biomolecules and compounds.


NMR spectrometer is crucial in metabolomics studies (metabolomics is the large-scale study of small molecules, commonly known as metabolites, within cells, biofluids, tissues or organisms.



Person In Charge:
Name : Dr. Azira Muhamad
Email : aziramuhamad@nibm.my
Tel No. 03-89267446
HTMLText_89F672E0_8749_9BB0_41D7_888025A991FE_mobile.html =
Finally quality sets of collected data are combined computationally with complementary chemical information to obtain and refine a model from the arrangement of atoms within the crystal.
Crystal structure is obtained from the final refined model and usually will be deposited in crystallographic database (such in Protein Data Bank).


Person In Charge:
Name : Dr. Mohd Anuar bin Jonet
Email : anuarjonet@nibm.my
Hp No. 03-89267446
HTMLText_992FA788_867F_FEF3_41C0_169D2C1119FB_mobile.html =
The RapidRAW technology is developed based on protein precipitation principle for fake honey/ sugar syrup differentiation. This product offers low cost option for fake honey screening and honey quality monitoring for industry and consumer.


Advantage:
• Simple technique
• Rapid result (2 minutes)
• Suitable for on-site monitoring
• Qualitative analysis
• Detect fake honey


Market potential:
1- Cytotoxicity assay
• To detect possible fake product


2- Food safety monitoring
• First line screening to differentiate fake product.
• Can be indicative for protein content in honey



Person In Charge:
Name : Mohd Razif bin Mamat/Dr Nor azfa Johari
Email : razif@nibm.my/azfajo@nibm.my
Hp No : 019-3280097
HTMLText_B1C9BF14_AE63_D02D_41D2_9B2E2F9FB7B1_mobile.html =
This laboratory is the preparative area for research involving structural study. The provides platform for processing sample from protein crude extracts. Different purification techniques will be applied to remove contaminants prior to crystallization experiment.




Person In Charge:
Name : Dr. Mohd Anuar bin Jonet
Email : anuarjonet@nibm.my
Tel No. 03-89267446
HTMLText_B986BA06_AE22_502D_41DF_6F3D5FB46DC9_mobile.html =
We promote advancements in biology by providing researchers complete genomic solutions using state-of-the-art DNA and RNA analysis instruments. The instrument available range from traditional capillary sequencing (Sanger Technology) to next-generation sequencing (Illumina MiSeq® System). The facility is perfectly suited to cater your project needs whether whole genome sequencing (WGS), transcriptome sequencing, amplicon-based projects, metagenomics as well as targeted sequencing.


Illumina MiSeq® System
• Suitable for targeted gene sequencing, metagenomics, small genome sequencing, targeted gene expression, amplicon sequencing and library QC.
• Variable options suitable to any application with generation of raw data up to 15 Gb of output with 25 M sequencing reads and 2x300 bp read lengths.


Sanger DNA Sequencing
• The Applied Biosystems 3730xl is a fully automated system used for detecting fluorescently labelled DNA and can provide up to 800 high quality bases per reaction.
• Ideal for single sample sequencing, primer walking, shotgun sequencing SNP detection & genome finishing.


Person In Charge:
Name : Irni Suhayu Sapian
Email : suhayu@nibm.my
Tel No : 03-89267446
HTMLText_C9D3EF7A_8687_BA7C_41DF_8F860098093B_mobile.html =
X-ray diffractometer (XRD) is considered to be the most important tool for determining the three-dimensional crystal structures of atom and molecules at high-resolution.


Structures of biological macromolecular at the atomic resolution level will provide information of the atoms size and the length and types of chemical bonds.


Comprehensive information from X-ray crystallographic experiment will reveal the structure and function of many biological molecules, including vitamins, drug, protein, and nucleic acids, such as DNA.


Simple workflow in obtaining 3-dimensional structure of desired protein will start with:


1- Producing an adequate protein crystal with pure in composition.
2- The crystal is subsequently placed in finely focused monochromatic beam of X-rays.
3- The angle and intensities of diffracted X-rays are measured at different crystal orientations


Person In Charge:
Name : Dr. Mohd Anuar bin Jonet
Email : anuarjonet@nibm.my
Hp No. 03-89267446
HTMLText_B8BDAE7F_AD4E_1567_41C4_BE2D5DB5A28F.html =
This lab is established as one of the impact from MOSTI Social Innovation project secured in 2015, focusing on stingless bee honey metabolite research. Since then, the lab has handled more than 2,000 rapid honey screening for industrial and public customers and expanding to other types of bioproducts.


a) The lab conduct tests for BioCompound Data Sheet (BioCDS) development:
• RapidRAW honey screening
• Metabolite profiling of honey and result alignment with CODEX and MS 2683:2017
• Identification of major microbial content in honey product
• Metabolite profiling of supplement products
• Cytotoxicity assay
• DPPH radical scavenging assay


b) The lab can provide consultation for:
• Cytotoxicity assay
• Biosensor development



Person In Charge:
Name : Mohd Razif bin Mamat/
Dr Nurul Ain A. Talib
Email : razif@nibm.my/
aintalib@nibm.my
Hp No : 019-3280097
HTMLText_B8BDAE7F_AD4E_1567_41C4_BE2D5DB5A28F_mobile.html =
This lab is established as one of the impact from MOSTI Social Innovation project secured in 2015, focusing on stingless bee honey metabolite research. Since then, the lab has handled more than 2,000 rapid honey screening for industrial and public customers and expanding to other types of bioproducts.


a) The lab conduct tests for BioCompound Data Sheet (BioCDS) development:
• RapidRAW honey screening
• Metabolite profiling of honey and result alignment with CODEX and MS 2683:2017
• Identification of major microbial content in honey product
• Metabolite profiling of supplement products
• Cytotoxicity assay
• DPPH radical scavenging assay


b) The lab can provide consultation for:
• Cytotoxicity assay
• Biosensor development



Person In Charge:
Name : Mohd Razif bin Mamat/
Dr Nurul Ain A. Talib
Email : razif@nibm.my/
aintalib@nibm.my
Hp No : 019-3280097
HTMLText_1E18123C_57F1_802D_41D2_B0CD0D6533F4_mobile.html =
___
LOREM IPSUM
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LOREM IPSUM
DOLOR SIT AMET
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JOHN DOE
Licensed Real Estate Salesperson


Tlf.: +11 111 111 111
jhondoe@realestate.com
www.loremipsum.com



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HTMLText_1E18423C_57F1_802D_41C4_458DB7F892AC.html =
JOHN DOE
Licensed Real Estate Salesperson


Tlf.: +11 111 111 111
jhondoe@realestate.com
www.loremipsum.com



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Company Name
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Liquid samples in NMR tube placed inside the 24-sample automation system for insertion and ejection of samples
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NMR is a technique to observe local magnetic fields around atomic nuclei. The sample is placed in a magnetic field and the NMR signal is produced by excitation of the nuclei sample with radio waves, which is detected with radio receivers. Certain atoms' nuclei have certain magnetic properties when in a strong magnetic field. Atoms like carbon, hydrogen, and fluorine can be detected in this way.
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One of the application of metabolomics NMR is in honey authenticity. Real raw honey can be differentiated with an adulterated or artificial honey based on the NMR spectra of each honey.
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Honey & Bioproduct Test Lab RapidRAW kit
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Honey & Bioproduct Test Lab
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Structural Biology & X-ray Crystallography Lab
HTMLText_A281FCE3_874A_AFB0_41CE_686BA18706A3.html =
Nuclear Magnetic Resonance (NMR) Spectroscopy
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Nuclear Magnetic Resonance (NMR) Spectroscopy
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Nuclear Magnetic Resonance (NMR) Spectroscopy
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Nuclear Magnetic Resonance (NMR) Spectroscopy
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Sequencing
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X-RAY DIFFRACTOMETER
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X-RAY DIFFRACTOMETER
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Company Name
www.loremipsum.com
info@loremipsum.com
Tlf.: +11 111 111 111
HTMLText_9BF7F054_877B_B690_4188_96178E1282CC_mobile.html =
Liquid samples in NMR tube placed inside the 24-sample automation system for insertion and ejection of samples
HTMLText_A2810CE6_874A_AFB0_41D1_90D335E98B8A_mobile.html =
NMR is a technique to observe local magnetic fields around atomic nuclei. The sample is placed in a magnetic field and the NMR signal is produced by excitation of the nuclei sample with radio waves, which is detected with radio receivers. Certain atoms' nuclei have certain magnetic properties when in a strong magnetic field. Atoms like carbon, hydrogen, and fluorine can be detected in this way.
HTMLText_A3067C1B_877A_6E90_41DB_B9F6766A63AF_mobile.html =
One of the application of metabolomics NMR is in honey authenticity. Real raw honey can be differentiated with an adulterated or artificial honey based on the NMR spectra of each honey.
HTMLText_99293772_867F_FE17_41D4_BC17A124702B_mobile.html =
Honey & Bioproduct Test Lab RapidRAW kit
HTMLText_A3BB2B38_B3F5_EA91_41CE_499C0ACE0706_mobile.html =
Honey & Bioproduct Test Lab
HTMLText_B1C76EFF_AE63_D1DB_41E1_BC7969E9E23A_mobile.html =
Structural Biology & X-ray Crystallography Lab
HTMLText_A306EC19_877A_6E90_41D6_DCFC6B5692D5_mobile.html =
Nuclear Magnetic Resonance (NMR) Spectroscopy
HTMLText_A281FCE3_874A_AFB0_41CE_686BA18706A3_mobile.html =
Nuclear Magnetic Resonance (NMR) Spectroscopy
HTMLText_9E260730_8749_9A90_41D7_24E5E56A8F43_mobile.html =
Nuclear Magnetic Resonance (NMR) Spectroscopy
HTMLText_8ACD5C15_AE6E_502F_41D7_D4BEE5706E27_mobile.html =
Nuclear Magnetic Resonance (NMR) Spectroscopy
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Sequencing
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X-RAY DIFFRACTOMETER
HTMLText_89FBC2CF_8749_9BF0_41D6_7C1677D719D7_mobile.html =
X-RAY DIFFRACTOMETER
HTMLText_98634CB9_AE23_D067_41AA_27B60631EFB3_mobile.html =


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National Institutes of Biotechnology Malaysia (NIBM)
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{{subtitle}}
National Institutes of Biotechnology Malaysia (NIBM)
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