- National Institutes of Biotechnology Malaysia
At a glance…
In 2005, the National Biotechnology Policy (NBP) was launched with the aim to make biotechnology as a new economic engine for the country. Among the many initiatives taken was to upgrade the three biotechnology cooperative centers (BCC) set up in 2002 into National Biotechnology Institutes in 2006. The BCCs were then named as Malaysian Institute of Pharmaceuticals & Nutraceuticals (IPHARM), Agro-Biotechnology Institute Malaysia (ABI), and Malaysia Genome Institute (MGI).
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- CEO & Director Messages
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"We Bring Science in Biotechnology to the Marketplace Through the Nurturing Of Biotech Companies and Creation of A Holistic Ecosystem For The Industryβs Growth"
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" Biology is the study of the complex things in the Universe. Physics is the study of the simple ones. If physics and biology one day meet, and one of the two is swallowed up, that one will be biology. "
- Research Project
| No. | PROJECT TITLE | Duration |
| Malaysia Genetics and Living Culture Collection: Safeguarding Research, Development, Innovation And Commercialization Of Biological Materials (NEW) | 1 year (2020) | |
| 2.Β | Program Pembangunan Mampan Benih Rumpai Laut Bagi Industri Aquakultur | 3 years (2018-2020) |
| 3. | COMMERCIALISING AN INTEGRATED AAALAC ACCREDITED SPF SMALL LABORATORY ANIMALS BREEDING AND NON-CLINICAL STUDIES RESEARCH CENTRE | 4 years ( 2017-2021) |
| 4. | Establishment of a technology platform for pharmaceuticals, nutraceuticals and cosmeceuticals product development and national natural product repository R&D&C | 2 years 2016-2018 |
DSTIN FLAGSHIP Program/ Pre-Commercialisation Projects (10th MP)
| No. | PROJECT TITLE | Duration |
| 1. | New Technologies for sustainable Bio-Economy : Construction of microbial Cell Biocatalyst for Production of Biobased Fine Chemicals. | 2 years |
| 2. | Enhancing The therapeutic potential of rAF Newcastle Disease Virus Cancer Vaccine. | 2 years |
| 3. | Development of a natural products library from Malaysian biodiversity for systematic discovery of potential active therapeutic agents for obesityΒ | 3 years |
| 4. | Drug-drug and Drug-herb interactions screening platform, a comprehensive high throughput safety testing service for drugs, nutraceuticals and standardized herbal medicine in IPharmΒ | 3 years |
| 5. | Development, Evaluation And Integration of Innovative Tools To Reduce Dengue Morbidity And Mortality In CommunityΒ | 3 years |
| 6. | Enhancing the Productivity of Farm Buffalo (Bubalus Bubalis) Through Modification of Rearing Practices | 3 years |
INTERNATIONAL COLLABORATION
| No. | PROJECT TITLE | COLLABORATOR |
| 1. | Structural Genomics of the Extremophilic Microbes Leucosporidium antarticum and Bacillus lehensis G1 | Monash UniversityΒ (Prof. Jamie Rossjohn) |
| 2. | New Technologies for Sustainable Bio-Economy: Construction of Microbial Cell BioCatalyst for Production of Biobased Fine ChemicalsΒ | Concordia University, Montreal, Canada (Prof. Adrian Tsang) |
MOSTI SOCIAL INNOVATION (MSI)
| No. | PROJECT TITLE | Year |
| 1. | Penentuan Profil Metabolite Madu Kelulut | Β 2015 |
| 2.Β | Teknologi DNA & GPS Terhadap Koloni Kelulut | 2016 |
| 3. | Projek The Innovative βeco- βCLEANββ Support Program | 2015 |
| 4.Β | Projek The Natural Cosmeceutical Formulation Workshop | 2015 |
| 5.Β | Projek The Eco-candle Making | 2015 |
| 6. | Cosmeceutical workshop with Cymbopogon nardus: Natural Product Invention | 2017 |
| 7. | Smart System Mushroom House for Oyster Mushroom Cultivation | 2015 |
| 8. | Pembangunan Sistem Fertigasi Bagi Penanaman Tanaman Herba Kaempferia parviflora Secara Berskala Besar | 2015 |
| 9. | Program Teknologi Kultur Tisu Tumbuhan Untuk Usahawan Muda Dalam Meningkatkan Ekonomi di Tuaran, Sabah | 2016 |
| 10. | Program Pembangunan Usahawan Desa Dalam Penanaman Cendawan di Kimanis, Papar, Sabah | 2016 |
| 11. | Program Penghasilan Makanan Ternakan Ruminan Kos Rendah dan Mampan Menggunakan Teknologi Silaj oleh Komuniti di Kawasan Padang Terap, Kedah | 2017 |
| 12. | Program pengeluaran benih kumpulan halia (Zingiber spp.) menggunakan teknik tisu kultur dan sistem fertigasi. | 2017 |
| 13. | Ternakan Ikan Patin Dalam Tangki Modular Terkawal | 2017 |
FUNDAMENTAL RESEARCH GRANT SCHEME (FRGS)-MOE
| No. | PROJECT TITLE | Year |
| 1. | Identifying the Novel Features of Diacylglyceryl Transferase (LGT) Membrane Enzyme in Leptospirosis β causing bacteria | 2019-2021 |
| 2. | Elucidation Of Crystal Structure And Function Of Enzymes With Phenol Removing Activity From Geobacillus. | 2019-2022 |
| 3. | Elucidation of the Mechanism of Action And Signal Transduction Pathway Activated by Two Natural Compounds with Anti- Diabetic Potential | 2017-2020 |
| 4. | Isolation and structure elucidation of bioactive compound(s) from khaya senegalensis (DESR.) A. Juss. Leaves with wound healing activityβ | 2019-2021 |
| 5. | Mechanistic studies on the mode of actions of standardised bilimbi fraction and its natural compounds in brown fat differentiation program | 2019-2021 |
| 6. | Iron Biofortification Of Malaysia Rice Using Targeted Genome Editing Approach | 2014-2016 |
| 7. | Development Of New Strains Of Tiger Milk Mushroom (Lignosus Sp) | 2014-2016 |
| 8. | Determination the Effects of Indigenous Silage Bacteria and Its Associated Bacterial Communities using Conventional and Next Generation Sequencing Approaches Towards Improved Silage Quality | 2018-2020 |
SMARTFUND (MESTECC)
| No. | PROJECT TITLE | Year |
| 1. | RapidRAW Screening Technology: Fake Honey Detection | 2019-2021 |
MOSTI SPECIAL ALLOCATION
| No. | PROJECT TITLE | Year |
| 1. | Large scale production of tuber of Tigerβs Milk Mushroom (Lignosus rhinocerus) | 2015-2017 |
| 2. | Identification Of The Growth And Development Of Termitomyces Heimii | 2015-2017 |
| 3. | Proteomics Of Termitomyces heimii At Different Developmental Stage | 2015-2017 |
| 4. | Smart System For Shiitake Mushroom (Lentinula edodes) Cultivation | 2015-2017 |
| 5. | Development of Nutraceutical and Pharmaceutical Products for Therapeutic Indications or Disease of High Burden to MalaysiaΒ | 2015-2018 |
GRANT AWARD
| No. | PROJECT TITLE | Year |
| 1. | Skim Sequencing Of 96 Heterotrigona Itama Genome (Grant Award by Illumina 2017) | 2017-2018 |
LOCAL RESEARCH COLLABORATION
| No. | PROJECT TITLE | LEAD BY |
| 1. | Genome Sequencing of local isolates bacteria Lysinibacillus sp. and Enterobacter sp. | UKM |
| 2. | Analisis Mikrobiom yang Terlibat dalam Patogenesis Ganoderma Boninense Terhadap Pereputan Pangkal Batang Pokok Kelapa Sawit, Elaeis guineensis | UKM |
| 3. | Molecular Characterization of Familial Hypercholesterolemia (FH) in a Malay Population via Exome Sequencing | UMBI |
| 4. | Proteomics Footprinting of Tecotrienols-treated Human Breast Cancer Cells. | UM |
| 5. | Genomic Diversity of Malaysian Aborigine (Orang Asli). | UMBI |
| 6. | Genome and transcriptome analyses of four Burkholderia pseudomallei isolated from Malaysia | UKM |
| 7. | Genome Sequencing and Analysis of Rhodococcus sp. | UNISEL |
| 8. | Comparative Genome Analyses and Phylogenomics Studies of Land and Marine Iguanas from the Galapagos Island | UKM |
| 9. | Functional characterization of hypothetical protein from Burkholderia pseudomallei | UKM |
| 10. | Structural Elucidation of Human APOBEC3B, a Cytosine Deaminase implicated in Cancer | UTM |
| 11. | Elucidation of the Neuro – Regenerative Signaling Pathway in Diopatra Claparedii | UMT |
| 12. | Unraveling the enzymes involved in dimerization of resveratrol. | UiTM |
| 13. | Pemuliharaan Genetik Kelip-kelip Pteroptyx tener (Coleoptera: Lampyridae) di Kuala Selangor | FRIM |
| 14. | Generation and Characterization of The Rafflesia Genome Sequence | UKM |
| 15. | Soil microbiome analysis of oil palm for potential Basal Stem Rot disease control | UPM |
| 16. | Comparative Genomics Of Rafflesia | UKM |
| 17. | Highland Stingless Bee Identification And The Assessment Of Domesticated Stingless Bee At High Altitude | UKM |
| 18. | Functional Studies of Mating Pheromones in Oil Palm Pathogen, Ganoderma boninense to Elucidate Its PathogenicityΒ | UKM |
| 19. | Targeted genomic Profile of Malay B-Thalassemia Patients by Using NGSΒ | USM |
| 20. | Penghasilan Madu Premium Berasaskan Inovasi Mustafa-Hive dan Hilda-Sistem | USM |
| 21. | Determination of Molecular Characteristics and Cytotoxicity of Polyphenol from Aquilaria sp. (Gaharu) as Lipase Inhibitor in Obesity Treatment | UPSI |
| 22. | Visualization model of biocatalysis remediation by polycyclic aromatic hydrocarbons-degrading enzymes through functional and structural characterization | UPSI |
| 23. | Elucidation of structure and function of conserved hypothetical proteins related to thermal stress response in psychrophilic bacterium and yeast | UMS |
| 24. | Mangosteen research sustainability using multi-omics integration and database development | UKM |
| 25. | Projek FRGS-MRSA: Characterisation of nonporous biochar-derived adsorbents from tropical biomass | UPM |
| 26. | Insights into the evolution of fiddler crab through whole genome comparison between Uca rosea with Uca annulipes | USM |
| 27. | Role of recombinant protease derived from Malaysian belacan on eschar and biofilm removal for necrotic wound healing | UTM |
| 28. | PCOS analysis | LPPKN |
| 29. | Cell Permeability and Bioavailability Evaluation of Citropten and its Anti-Inflammatory Properties in a RatΒ Model Inflammation | IMR |
| 30. | Oral pharmacokinetic evaluation of freeze-dried Carica papaya leaves juice formulations in ratsΒ | IMR |
| 31. | The Possible Use of Mitochondria as Indicator in Production Yield and Abnormality of Oil Palm | MPOB |
| 32. | Traceability and Authenticity of Honey and Kelulut Honey | BKKM (MOH) |
| 33. | Development of entomopathogenic fungi as biocontrol agents against dengue vectors | Swinburne University of Technology Sarawak Campus |
| 34. | Fitness assessment of dengue diagnostic methods for safe utilisation | UM |
| 35. | Safety of blood and tissues supply | UM |
| 36. | Dengue in marginalized populations | UM |
| 37. | Point of care test (POCT) for Dengue | UM |
| 38. | An integrated microfluidics system for rapid serotype-specific detection of dengue virus infection | UM |
| 39. | Development of New Tools for the Diagnosis and Management of Dengue in Local Communities (CLINICAL) | Monash University |
| 40. | Multi-Centre Field Trial diagnostic Kit for the Identification of potential severe dengue (PARA CLINICAL) | UM |
| 41. | Production and trial use of Spokojan (Community Empowerment) | UM |
| 42. | Design and synthesize lead compounds for anti-dengue based on the bioactive natural products and novel L-thionucleoside pyrimidine analogues using Vorbruggen Coupling Method | UKM/USM |
| 43. | Elucidation of Immune modulatory molecules from Carica papaya extract against Dengue fever | USM |
| 44. | Investigation of the effects of natural products in reducing the progression of atherosclerosis | UMT |
| 45. | Progressing towards discovery of anti-infective entities from natural product: Elucidation of pathways involved in anti-infective using the Caenorhabditis elegans model system | USM |
| 46. | Development of a natural products library from Malaysian biodiversity for systematic discovery of potential active therapeutic agents for obesityΒ | UKM, USM, UM |
| 47. | Molecular Biopharming of Nipah Virus Surface Antigens for The Production of Recombinant Vaccine | MARDI |
| 48. | Development of Vaccines Against H5N1 and Characterization of The Vaccine Induced Immune Responses and Immunity | UPM |
| 49. | Advanced Reproductive Biotechnology of Seladang and Banteng | MARDI |
| 50. | Application of Advanced Reproductive Biotechnologies for Breeding and Mass Propagation of Malayan Porcupine (H. brachyurus) | PERHILITAN |
| 51. | Genetic Characterization and Intensive Breeding of Malaysian Barking Deer (Kijang) in Developing It As An Alternative Food Source, A Model for Ruminant Health Research and Agro-tourism | UPM |
| 52. | Development and Evaluation of Fermented PKE Based Feed for Poultry and Fish | MARDI |
| 53. | Bio-processed OPF as animal feedΒ | MARDI |
| 54. | Bio-processed Palm Oil Mill Effluent (POME) for Poultry Feed | MARDI |
| 55. | Development of A Recombinant Single Cell Protein Organism Capable of Bio-synthesizing High Unsaturated Fatty Acids as Feed for Aquaculture | USM |
| 56. | Phylogenetics and Molecular Characterization of The Variant Surface Glycoproteins (VSGs), and Antigenic Repertoire of Trypanosoma evansi in Malaysia | UPM |
| 57. | Process Improvement Of Newcastle Disease Virus (NDV) Vaccine Production In Bioreactor | IIUM |
| 58. | Development of Diagnostic Kit for Detection of Nodavirus from Aquaculture Marine Fish | UMS |
| 59. | Molecular Epidemiology and Pathogenesis of Streptococcus Infection in Caged-cultured Freshwater Fishes | FRI |
| 60. | Production Red Fermented Rice as An Alternative for Feed Ingredients for Development Low Cholesterol Eggs and Low Cholesterol Prawns | MARDI |
| 61. | Reproductive, Breeding and Culture Technologies for Commercial Production of Kelah, Tor spp. | UPM |
| 62. | Development of Antioxidant-rich Products from Local Fruits | MARDI |
| 63. | Molecular Markers for Quality Control of Clonal Oil Palm | MPOB |
| 64. | Tissue-specific Regulatory Sequences and Transcription Factors from Oil Palm for Plant Genetic Engineering | UPM |
| 65. | Genomics and Gene Discovery in Rubber | LGM |
| 66. | Discovery of New Genes from Plants using Genomics And Bioinformatics | MARDI |
| 67. | Suppression and Control of the Spread of Ganoderma Infection In Oil Palm | UPM |
| 68. | Physiological Manipulations to Stabilize and/or Increase Bioactive Compounds in Phyllanthus sp. for Its Antiviral and Other Health Related Properties | MARDI |
| 69. | Identification of Yield Related QTLs and Genes for Improvement of Malaysian Rice Cultivars | UKM |
| 70. | Enhancement of Yield Potential of Malaysian Rice Through Incorporation of Photosynthetic Specific Genes from Echinochloa crus-galli | MARDI |
| 71. | Production of Mass Culture Organism as Live Feed – Development of Photo-bioreactor for High Density Cell Cultivation of Marine Algae for Subsequence Use as Live Feed for Marine Fish Larviculture | UNISEL |
| 72. | Multivariate Biotechnology Approaches with Artificial Propagations, Stock Enhancement for Sustainable Exploitation & Commercialization of Malaysians Stichopus spp. | USM |
| 73. | Mass Fry Production Technology of Epinephelus sp (Grouper) | UKM |
| 74. | Biotechnology and Genetics for the Improvement of The Malaysia Giant Freshwater Prawn (Macrobrachium rosenbergii) | UMS |
| 75. | Development of corn silage based feed for beef cattle production | UPM |
| 76. | Development of solid state and submerged fermentation technology for the production of Schizophyllum commune | IIUM |
| 77. | Metabolomic study for The Development of Functional Foods with Anti-Diabetic Property | UPM |
| 78. | Development of Bioactive Peptides as Food Ingredients from High-Protein Materials Using Nanocarrier Technology | UPM |
| 79. | Bovine Sperm Sexing Using Flow Cytometry and Immunological Approaches | UM |
| 80. | Development of Multiple Separation Techniques for High Fertilizing Capacity Bovine | UKM |
| 81. | Evaluation of Bali cattle meat quality through biotechnological approach | UPM |
- Event / Announcements
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